The Parental Analgesia Slide is a new device developed with the objective of improving parental dosing accuracy.
In this prospective, randomized study, 160 parents accompanying children aged between one and 13
years old were randomly allocated to complete a paracetamol dose calculation and administration questionnaire using one of two sources of prescribing information. Absolute percentage dose error and the number of correct dosage intervals, frequencies, and demonstrated drug volumes were compared.
Use of the Parental Analgesia Slide resulted in a reduction in the absolute percentage dose error from a median of 33.3 to 0% (P < 0.001) and an increase in the number of correct dosage intervals and frequencies (59/80 to 70/80, P = 0.046). There was no difference in the number of correctly demonstrated drug volumes (P = 0.082) despite a greater number of parents Pitavastatin opting to use an oral syringe rather than a dosing spoon when using the Slide (24/80 to 44/80, P = 0.002).
The Parental Analgesia Slide resulted in improved parental ability to calculate paracetamol
dose, interval, and frequency while preserving their ability to demonstrate an accurate drug volume.”
Spinal anesthesia (SA) is widely used for awake regional anesthesia in ex-preterm infants scheduled for herniotomy. Awake caudal anesthesia (CA) is suggested as an alternative approach for these patients and type of surgery. The aim of this study was to compare efficacy and complications of the two different techniques.
Two historical populations of 575 ex-preterm infants undergoing herniotomy under awake SA (n = 339; 1998-2001) and under awake CA (n = 236; CUDC-907 nmr 2001-2009) were investigated. Data are compared using t-test and chi-square tests (P < 0.05).
The SA group consisted of 339 patients, they were born after 32.0 (3.3) weeks of gestation on average with a mean birth weight of 1691 this website g (725). The CA group consisted of 236 patients born after 32.1 weeks (3.7) with a mean
birth weight of 1617 g (726). At the time of operation, the total age was 41.37 (3.6) and 41.28 (4.0), respectively, for SA and CA patients, and the corresponding weights were 3326 (1083) g and 3267 (931) g for SA and CA patients, respectively. For SA, significantly more puncture attempts were needed (1.83 vs 1.44, P < 0.001). Surgery was performed under pure regional anesthesia in 85% (SA) and 90.1% (CA) (ns). A change to general anesthesia was necessary in 7.7% (SA) and 3.9% (CA) (ns). Overall, intra- and postoperative complications were not statistically different.
Caudal anesthesia was shown to be technically less difficult than SA and to have a higher success rate. Its application as awake regional anesthesia technique in these patients seems more appropriate than SA.”
Propofol is a popular agent for providing procedural sedation in pediatric population during lumbar puncture and spinal anesthesia.