Cellular expression of FoxP3 was evident in 71% of benign and 91.9% of malignant tissues. The nuclear
and cytoplasmic expression patterns were quantified separately. A multivariate logistic regression analysis indicated that cytoplasmic FoxP3 expression is an independent risk factor for thyroid malignancy. Cytoplasmic FoxP3 staining was inversely correlated with patient age. Nuclear FoxP3 staining was more intense in younger patients and in tumors presenting with metastasis at diagnosis. FoxP3+ lymphocytes were more frequent in tumors smaller than 2 cm, those without extrathyroidal invasion, and in patients with concurrent chronic lymphocytic thyroiditis.
CONCLUSIONS: We demonstrated FoxP3 expression in differentiated thyroid carcinoma cells and found evidence that this expression may exert an important
influence on several features of tumor aggressiveness.”
“Objective: check details To describe the clinical course, diagnostic features and management of a case of reversible posterior leukoencephalopathy syndrome after a lateral cranial base removal.
Patient: A 58-year-old male patient with an inconspicuous clinical history presented with a lethargic state without localized neurologic deficit in the postoperative period of a subtotal petrosectomy for an adenoid cystic carcinoma of the temporal bone.
Interventions: Cranial T2-weighted magnetic resonance imaging showed increased signal intensity in the occipital and cerebellar regions, centered at the cortical and subcortical white matter. Antihypertensive drugs, anticonvulsants, www.selleckchem.com/products/sch772984.html and antibiotics were administered. A complete resolution of the symptoms and radiologic findings were achieved within 1 to 2 weeks.
Results: The clinical presentation, radiologic findings, and
resolution of the clinical setting are consistent with a diagnosis of reversible posterior leukoencephalopathy S63845 in vivo syndrome.
Conclusion: To our knowledge, this is the first report of reversible posterior leukoencephalopathy syndrome after a lateral cranial base surgery.”
“Objectives: Spinal cord injury (SCI) is a traumatic event that affects many facets of the injured people’s lives. One aspect is sexual functioning. The purpose of this study is to identify the sexual problems of women with SCI and determine their level of knowledge about sexuality.
Methods: Twenty-six women with SCI for longer than 6 months were evaluated. Demographic information, sexual experiences were surveyed. Patients were also asked if and how they received sexual health consultation after SCI. Female Sexual Function Index (FSFI) and Beck Depression Inventory were evaluated.
Results: In this study, average age of the women with SCI was 32.96 +/- 8.23 years (22-50 years). Eight patients had regular sexual intercourse while one married woman did not have any sexual relationship after SCI. Twenty-four of the patients in the study received no information about pregnancy or sexual health after SCI.