Setting. Nonspecific LBP is a common health problem in adolescence. Although some behaviors and socio-demographic factors are believed to contribute to the disorder, influential factors of LBP remain undefined. Moreover, until now there is no available information of influential factors for LBP in Chinese adolescents. Subjects. A total of 1,214 adolescents were involved in the study, including 607 cases with nonspecific LBP and 607 controls without history of nonspecific LBP. Outcome Measures. A self-administered questionnaire buy APR-246 was designed for epidemiological survey
to investigate the risk factors for nonspecific LBP. All cases and controls were investigated for their family histories of nonspecific LBP, physical
activities, sedentary activities, schoolbag weights, school performances, living conditions, and etc. Method. A 1:1 matched case-control study was conducted on 1,214 adolescents from an elementary school and a secondary school in Guangzhou City, southern China. Results. Family history (odds ratio [OR] 2.57, 95% confidence interval [CI] 1.853.58), long duration of carrying schoolbag (OR 1.38, 95% CI 1.111.72) and rest position between classes (OR 1.18, 95% CI 1.011.39) were positively GNS-1480 concentration correlated with self-reported nonspecific LBP. Students regularly playing basketball (OR 1.58, 95% CI 1.092.30) was found to be significantly more likely to have LBP. Also, students who
feel schoolbag uncomfortable (OR 1.38, 95% CI 1.111.72) was found to experience more LBP. Conclusions. Family history, feeling schoolbag uncomfortable, duration of schoolbag carrying, basketball playing and rest position between classes are the major risk factors for nonspecific LBP in adolescents.”
“Objective: The aim of this study was to investigate CH5424802 mouse the connections between multiple sclerosis (MS) and fertility, pregnancy.
Methods: The case histories and pregnancy complications in a sample of 65 treatment-naive pregnant women with MS in the period 1998-2012 were compared with an age-matched case-controlled analysis. Comparisons were made between primigravidas and multigravidas subjects.
Results: Our results revealed a higher rate of miscarriage (18.46%) in the first trimester in women with MS, and intrauterine death (7.69%) in the third trimester, as compared with women without MS (p<0.001 and p = 0.035).
Conclusions: These findings suggest that, the risk of miscarriages and intrauterine death may be disease-related not drug-related feature. Further studies are needed to determine to possible associated factors of miscarriages.”
“Background – Mutations in the LMNA gene, encoding lamins A/C, represent a significant cause of dilated cardiomyopathy. We recently identified 18 protein-altering LMNA variants in a cohort of 324 unrelated patients with dilated cardiomyopathy.