Factors contributing to a MRHA identified in this study are all important considerations for medicines optimisation in this vulnerable patient Trametinib group. Direct referral to pharmacists from GPs and practice nurses within the primary healthcare setting is one way by which this patient group can be supported to optimise their medicines use. A limitation to this study is the small sample size of patients recruited and thus further investigation would be required to substantiate this finding. 1. Hallas J, Harvald B, Gram LF, Grodum E, Brosen K, Haghfelt T et al. Drug related hospital admissions: the role of definitions and intensity of data collection, and the possibility of prevention.

Journal of Internal Medicine 1990; 228: 83–90. 2. Gordon K., Smith F, Dhillon S. The development and validation of a screening tool for the identification of patients experiencing medication-related problems. IJPP 2005; 13: 187–193. J. Desborough, D. Somally, selleck products on behalf of the CAREMED management group University of East Anglia, Norwich, UK Multi-professional medication reviews have the potential to improve the quality of prescribing in care home residents Nearly all care home residents (91%) had at least one intervention with an average of four interventions per resident following the review Residents

identified as needing a further review or with medication changes were more likely to be admitted to hospital in the 6 months following the multi-professional medication review More responsive models of care are needed to support GPs to prevent hospital admissions in complex care home residents. With a growing population of older people residing in care homes and recognised sub optimal medicines management, there is a need to develop services to better support residents. The CAREMED study was an RCT of a multi-professional medication review service in 30 care homes for older people(1). The aims of this study were to explore the interventions made during the first medication review in

the intervention arm of the CAREMED trial and identify any relationships with patient outcomes Tyrosine-protein kinase BLK of falls and hospital admissions. The CAREMED study was a cluster randomised controlled trial in 30 care homes for older people. This sub-analysis extracted data from all intervention residents’ first medication review including demographics, medication and medical conditions. Details of the interventions made during the review were extracted and categorised. Regression analysis was used to identify any relationships between the individual intervention categories and the outcomes of falls and emergency hospital admissions in the 6 months following the review. Ethical approval was granted from NHS research ethics. Three hundred twenty (90%) residents had at least one medication where the multidisciplinary team recommended an intervention.