aeruginosa and P. putida that generated significant

new insight into the underlying biology of these important organisms. Through this work, we provide a novel methodology for reconciling models, present new genome-scale reconstructions of P. aeruginosa and P. putida that can be directly compared at a network level, and perform a network-wide comparison of the two species. These reconstructions provide fresh insights into the metabolic similarities and differences between these important Pseudomonads, and pave the way towards full comparative analysis of genome-scale metabolic reconstructions of multiple species.”
“A growing body of experimental evidence gathered in the last 10-15 years with regard to targeted and non-targeted effects of low doses of ionizing radiation (hyper-radiosensitivity, induced

radioresistance, adaptive response, genomic instability, bystander effects) has pushed the radiobiology Citarinostat research towards a better understanding of the mechanisms underlying these phenomena, the extent to which they are active in-vivo, and how they are inter-related. In such a way factors could be obtained and included in the estimation of potential cancer risk to the human Population of exposure to low levels of ionizing radiation. Different experimental approaches have been developed and employed to study such effects in-vitro (medium transfer experiments; broad-field irradiation at low doses also with insert or shielding systems…). In this regard,

important contributions came from ionizing radiation microbeam facilities that turn to be powerful tools to perform selective irradiations of individual cells inside selleck kinase inhibitor a population with an exact, defined and reproducible dose (i.e. number of particles, in case of charged particle microbeams). Over the last 20 years the use of microbeams for radiobiological applications increased substantially and a continuously growing number of such facilities, providing X-rays, electrons, light and heavy ions, has been developing all over the world. Nowadays, learn more just in Europe there are 12 microbeam facilities fully-operational or under-development, out of more than 30 worldwide. An overview of the European microbeam facilities for radiobiological studies is presented and discussed in this paper.”
“Single-phase rock-salt CdZnO films were synthesized on r-plane sapphire substrates by metal-organic chemical vapor deposition. Evolutions in growth orientations were investigated in these films as a function of Zn content and film thickness. The preferred orientation is found to black (thick) and red (thin) lines depend on the balance between the surface and strain energy accumulated in the films in accordance with the so-called overall energy model. Specifically, (100) orientation dominates below a critical Zn content and/or a critical film thickness, otherwise (111)-oriented grains nucleate on top of the (100) planes. (C) 2011 American Institute of Physics. [doi: 10.1063/1.